DNA Technology
DNA testing uses Polymerase Chain Reaction (PCR) technology to detect certain pathogenic and opportunistic microorganisms present in blood. PCR, whether in a single assay or multiple assay (multiplex PCR) has allowed single detection or simultaneous detection and differentiation of multiple species of organisms in which the level of sensitivity and specificity is still unmatched by any other laboratory procedures. PCR assay has made it possible for clinicians to rapidly screen individuals for potentially pathogenic organisms such as Mycoplasma, eliminating the long agonizing waiting time.
Mycoplasma species have been implicated in a number of critical conditions. These include chronic fatigue syndrome, rheumatoid arthritis and gulf war syndrome. Community-acquired respiratory tract infections, and in particular atypical pneumonia, may be caused by either Chlamydia Pneumoniae or Mycoplasma Pneumoniae. One form possibly resulting in the need for hospitalization whereas the other may be responsible for long lasting disease. Rapid identification is recommended in order to administer the specific treatment required.
In Korea, 23 out of 56 samples collected from chronic gastritis patients were found positive for human mycoplasmas, which included: M. facium, M. fermentans, M. orale, M. salivarium and M. spermatophilum. Quick and accurate identification of the pathogen involved in the infection will result in more specific and better treatment.
Obsessive Compulsive Disorder (OCD), anorexia nervosa and/or tic disorder are currently designated criteria for paediatric autoimmune neuropsychiatric disorder (PANDAS) shown to be associated with Group A beta-hemolytic streptococcal infection. Group B streptococcai on the other hand, are known as an important cause of sepsis and meningitis in newborns and are associated with disease in pregnant women.
DNA for PCR analysis is extracted from both the RBC and WBC blood components not just white cell nuclei as in other procedures. We offer Mycoplasma species, Mycoplasma fermentans, Chlamydia species and / or Borrelia.
Patient Preparation:
No antibiotics or antimicrobial herbs to be taken for 4 weeks prior to collection
Type of Collection:
The most commonly tested sample is whole blood - taken by venipuncture, though testing on urine and tissue may also be requested.
Kits:
Kits are available for intra and interstate patients. Please enquire about the cost as it is not refundable.
Payment of the test cost is made when ordering the kit.
Please phone us on (02) 9283 0807 or contact us if you would like to order a kit.
back to top